human TMPO shRNA silencing Adenovirus

Name 
Ad-h-TMPO-shRNA
Cat No 
shADV-226002
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TMPO.

shADV-226002
Ad-h-TMPO-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TMPO (thymopoietin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CMD1T; lamina-associated polypeptide 2; LAP2; LEM domain containing 4; LEMD4; PRO0868; thymopoietin; thymopoietin beta; Thymopoietin isoform alpha; Thymopoietin, isoforms beta/gamma; thymopoietin-related peptide isoform alpha; thymopoietin-related peptide isoforms beta/gamma; TP; TP alpha; TP beta/gamma; TPRP isoform alpha; TPRP isoforms beta/gamma
Description (eCommerce)
LAP2 alpha beta gamma/TMPO may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane [taken from NCBI Entrez Gene (Gene ID: 7112)].
Description (Vector)
TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gene ID
7112
Gene Name (eCommerce)
thymopoietin
Gene Name (Vector)
thymopoietin
Gene Symbol
TMPO
HGNC ID
HGNC:11875
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
Protein Name (eCommerce)
Lamina-associated polypeptide 2, isoform alpha
RefSeq ID
NM_003276
RefSeq Synonyms
NM_003276, NM_001307975, NM_001032284, NM_001032283, BC053675,
Research Areas
Cardiology,Cardiomyopathy,Cardiovascular,Cell Cycle
Research Areas (Faceted)
cardiovascular,cell_biology,cell_cycle,genetics
Species
human
Target Sentence
LAP2 alpha beta gamma/TMPO may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane [taken from NCBI Entrez Gene (Gene ID: 7112)].
UniGene ID
Hs.11355
UniProt ID (eCommerce)
P42167

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.