human TLR2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TLR2.
shADV-225587
Ad-h-TLR2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TLR2 (toll like receptor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD282; TIL4
Description (Vector)
TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Gene ID
7097
Gene Name (Vector)
toll like receptor 2
Gene Symbol
TLR2
HGNC ID
HGNC:11848
ORF Size (aa)
2355
ORF Size (bp)
2355 bp
RefSeq ID
NM_003264
RefSeq Synonyms
NM_003264, NM_001318796, NM_001318795, NM_001318793, NM_001318791, NM_001318790, NM_001318789, NM_001318787, BC033756,
Species
human
UniGene ID
Hs.519033
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.