human TF shRNA silencing Adenovirus

Name
Ad-h-TF-shRNA

Cat No
shADV-225342

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TF.

shADV-225342

Ad-h-TF-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TF (transferrin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

beta-1 metal-binding globulin; epididymis secretory sperm binding protein Li 71p; HEL-S-71p; PRO1557; PRO2086; serotransferrin; siderophilin; TFQTL1; Transferrin

Description (eCommerce)

Transferrin is a glycoprotein responsible for the transport of iron through the bloodstream. Produced in the liver, its levels can act as a general readout for liver function and health.

Description (Vector)

TF encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.

Gene ID

7018

Gene Name (eCommerce)

Human transferrin

Gene Name (Vector)

transferrin

Gene Symbol

HGNC ID

HGNC:11740

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2097

ORF Size (bp)

2097 bp

Protein Name (eCommerce)

Serotransferrin

RefSeq ID

NM_001063

RefSeq Synonyms

NM_001063, BC059367,

Research Areas

HIF-1 Signaling,Mitochondrion,Signal Transduction

Research Areas (Faceted)

cell_biology,signal_transduction

Species

human

Target Sentence

Transferrin is a glycoprotein responsible for the transport of iron through the bloodstream. Produced in the liver, its levels can act as a general readout for liver function and health.

UniGene ID

Hs.518267

UniProt ID (eCommerce)

P02787

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.