human TES shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TES.
shADV-225314
Ad-h-TES-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TES (testin LIM domain protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TESS; TESS-2
Description (Vector)
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Gene ID
26136
Gene Name (Vector)
testin LIM domain protein
Gene Symbol
TES
HGNC ID
HGNC:14620
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
RefSeq ID
NM_015641
RefSeq Synonyms
NM_152829, NM_015641, BC001451,
Species
human
UniGene ID
Hs.664957
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.