human TBXAS1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TBXAS1.
shADV-225170
Ad-h-TBXAS1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TBXAS1 (thromboxane A synthase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS
Description (Vector)
TBXAS1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
6916
Gene Name (Vector)
thromboxane A synthase 1
Gene Symbol
TBXAS1
HGNC ID
HGNC:11609
ORF Size (aa)
1605
ORF Size (bp)
1605 bp
RefSeq ID
NM_001061
RefSeq Synonyms
NM_030984, NM_001314028, NM_001166254, NM_001166253, NM_001130966, NM_001061, BC041157, BC014117,
Species
human
UniGene ID
Hs.520757
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.