human TBCA shRNA silencing Adenovirus

Name 
Ad-h-TBCA-shRNA
Cat No 
shADV-225112
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TBCA.

shADV-225112
Ad-h-TBCA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TBCA (tubulin folding cofactor A). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CFA; chaperonin cofactor A; epididymis secretory sperm binding protein; TCP1-chaperonin cofactor A; Tubulin-folding cofactor A; tubulin-specific chaperone A
Description (eCommerce)
Tubulin-specific chaperone A (TBCA) is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state [taken from NCBI Entrez Gene (Gene ID: 6902)].
Description (Vector)
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A.
Gene ID
6902
Gene Name (eCommerce)
tubulin folding cofactor A
Gene Name (Vector)
tubulin folding cofactor A
Gene Symbol
TBCA
HGNC ID
HGNC:11579
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
327
Protein Name (eCommerce)
Tubulin-specific chaperone A
RefSeq ID
NM_004607
RefSeq Synonyms
NM_004607, NM_001297740, NM_001297738, BC105285, BC018210,
Research Areas
Cytoskeleton,Immunology,Metabolism/Metabolic Process,Protein Folding,Translational Control
Research Areas (Faceted)
cell_biology,immunology,metabolism,transcription_translation
Species
human
Target Sentence
Tubulin-specific chaperone A (TBCA) is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state [taken from NCBI Entrez Gene (Gene ID: 6902)].
UniGene ID
Hs.291212
UniProt ID (eCommerce)
O75347

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.