human SYN3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SYN3.
shADV-224806
Ad-h-SYN3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SYN3 (synapsin III). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
SYN3 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms.
Gene ID
8224
Gene Name (Vector)
synapsin III
Gene Symbol
SYN3
HGNC ID
HGNC:11496
ORF Size (aa)
1743
ORF Size (bp)
1743 bp
RefSeq ID
NM_003490
RefSeq Synonyms
NM_133633, NM_003490, NM_001135774, BC143874, BC117460, BC075066, BC075065,
Species
human
UniGene ID
Hs.608750
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.