human SUDS3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SUDS3.
shADV-224699
Ad-h-SUDS3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SUDS3 (SDS3 homolog, SIN3A corepressor complex component). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
45 kDa Sin3-associated polypeptide; SAP45; SDS3; sin3 histone deacetylase corepressor complex component SDS3; sin3A-associated protein, 45kDa; suppressor of defective silencing 3 protein homolog
Description (eCommerce)
SDS3 (suppressor of defective silencing 3 protein homolog) is a component of the Sin3 histone deacetylase corepressor complex. In this complex SDS3 interacts with SIN3A to regulate gene expression via chromatin modification. Studies in mice have shown SDS3 to be important to genomic stability.
Description (Vector)
SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 (PubMed 12724404)).(supplied by OMIM, Mar 2008)
Gene ID
64426
Gene Name (eCommerce)
SDS3 homolog, SIN3A corepressor complex component
Gene Name (Vector)
SDS3 homolog, SIN3A corepressor complex component
Gene Symbol
SUDS3
HGNC ID
HGNC:29545
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
987
Protein Name (eCommerce)
Sin3 histone deacetylase corepressor complex component SDS3
RefSeq ID
NM_022491
RefSeq Synonyms
NM_022491, BC098404, BC093990,
Research Areas
Apoptosis,Chromatin Remodeling,Epigenetic Regulation of Gene Expression,Histone Modification,Transcription Factor/Regulator
Research Areas (Faceted)
transcription_translation,cell_biology,genetics
Species
human
Target Sentence
SDS3 (suppressor of defective silencing 3 protein homolog) is a component of the Sin3 histone deacetylase corepressor complex. In this complex SDS3 interacts with SIN3A to regulate gene expression via chromatin modification. Studies in mice have shown SDS3 to be important to genomic stability.
UniGene ID
Hs.602312
UniProt ID (eCommerce)
Q9H7L9
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.