human STARD5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human STARD5.
shADV-224523
Ad-h-STARD5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human STARD5 (StAR related lipid transfer domain containing 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 (PubMed 12011452)).(supplied by OMIM, Mar 2008)
Gene ID
80765
Gene Name (Vector)
StAR related lipid transfer domain containing 5
Gene Symbol
STARD5
HGNC ID
HGNC:18065
ORF Size (aa)
642
ORF Size (bp)
642 bp
RefSeq ID
NM_181900
RefSeq Synonyms
NM_181900, BC004365,
Species
human
UniGene ID
Hs.513075
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.