human ST6GALNAC4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ST6GALNAC4.
shADV-224470
Ad-h-ST6GALNAC4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ST6GALNAC4 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IV; SIAT3-C; SIAT3C; SIAT7-D; SIAT7D; ST6GalNAc; ST6GALNACIV
Description (Vector)
ST6GALNAC4 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene.
Gene ID
27090
Gene Name (Vector)
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
Gene Symbol
ST6GALNAC4
HGNC ID
HGNC:17846
ORF Size (aa)
909
RefSeq ID
NM_175040
RefSeq Synonyms
NM_175040, NM_175039, BC036705,
Species
human
UniGene ID
Hs.3972
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.