human SRCAP shRNA silencing Adenovirus

Name 
Ad-h-SRCAP-shRNA
Cat No 
shADV-224311
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SRCAP.

shADV-224311
Ad-h-SRCAP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SRCAP (Snf2 related CREBBP activator protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DOMO1; EAF1; FLHS; SWR1
Description (Vector)
SRCAP encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features.
Gene ID
10847
Gene Name (Vector)
Snf2 related CREBBP activator protein
Gene Symbol
SRCAP
HGNC ID
HGNC:16974
ORF Size (aa)
9693
ORF Size (bp)
9693 bp
RefSeq ID
NM_006662
RefSeq Synonyms
NM_006662, BC172428, BC159099,
Species
human
UniGene ID
Hs.647334

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.