human SS18L1 shRNA silencing AAV

Name 
AAV-h-SS18L1-shRNA
Cat No 
shAAV-224377
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SS18L1.

shAAV-224377
AAV-h-SS18L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SS18L1 (SS18L1, nBAF chromatin remodeling complex subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CREST; LP2261
Description (Vector)
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.(supplied by OMIM, Jul 2002)
Gene ID
26039
Gene Name (Vector)
SS18L1, nBAF chromatin remodeling complex subunit
Gene Symbol
SS18L1
HGNC ID
HGNC:15592
ORF Size (aa)
1200
ORF Size (bp)
1200 bp
RefSeq ID
NM_198935
RefSeq Synonyms
NM_198935, NM_001301778, BC068993, BC034494,
Species
human
UniGene ID
Hs.154429

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.