human SPP1 shRNA silencing Adenovirus

Name 
Ad-h-SPP1-shRNA
Cat No 
shADV-224233
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human SPP1.

shADV-224233
Ad-h-SPP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SPP1 (secreted phosphoprotein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BNSP; BSPI; ETA-1; OPN
Description (Vector)
SPP1 is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
6696
Gene Name (Vector)
secreted phosphoprotein 1
Gene Symbol
SPP1
HGNC ID
HGNC:11255
ORF Size (aa)
864
RefSeq ID
NM_000582
RefSeq Synonyms
NM_001251830, NM_001251829, NM_001040060, NM_001040058, NM_000582, BC093033, BC022844, BC017387, BC007016,
Species
human
UniGene ID
Hs.313

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.