human SPAST shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SPAST.
shADV-224093
Ad-h-SPAST-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SPAST (spastin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADPSP; FSP2; SPG4
Description (Vector)
SPAST encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
Gene ID
6683
Gene Name (Vector)
spastin
Gene Symbol
SPAST
HGNC ID
HGNC:11233
ORF Size (aa)
1755
ORF Size (bp)
1755 bp
RefSeq ID
NM_014946
RefSeq Synonyms
NM_199436, NM_014946, BC150260,
Species
human
UniGene ID
Hs.468091
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.