mouse SPAST shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Spast.
shAAV-272936
AAV-m-SPAST-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Spast (spastin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mKIAA1083; Spg4
Description (Vector)
ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. May also play a role in axon growth and the formation of axonal branches.
Gene ID
50850
Gene Name (Vector)
spastin
Gene Symbol
Spast
ORF Size (aa)
1842
ORF Size (bp)
1842 bp
RefSeq ID
NM_016962
RefSeq Synonyms
NM_016962, NM_001162870, BC046286,
Species
mouse
UniGene ID
Mm.19804
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.