human SPANXC shRNA silencing Adenovirus

Name 
Ad-h-SPANXC-shRNA
Cat No 
shADV-224078
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human SPANXC.

shADV-224078
Ad-h-SPANXC-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SPANXC (SPANX family member C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C; CT11.3; CTp11; SPANX-C
Description (Vector)
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.
Gene ID
64663
Gene Name (Vector)
SPANX family member C
Gene Symbol
SPANXC
HGNC ID
HGNC:14331
ORF Size (aa)
294
RefSeq ID
NM_022661
RefSeq Synonyms
NM_022661, BC054023,
Species
human
UniGene ID
Hs.558533

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.