human SPANXC Over-expression AAV

Name 
AAV-h-SPANXC
Cat No 
AAV-224078
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SPANXC.

AAV-224078
AAV-h-SPANXC

Ready-to-use AAV expressing Human SPANXC (SPANX family member C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C; CT11.3; CTp11; SPANX-C
Description (Vector)
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.
Gene ID
64663
Gene Name (Vector)
SPANX family member C
Gene Symbol
SPANXC
HGNC ID
HGNC:14331
ORF Size (aa)
294
RefSeq ID
NM_022661
RefSeq Synonyms
NM_022661, BC054023,
Species
human
UniGene ID
Hs.558533

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.