human SNX2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SNX2.
shADV-223935
Ad-h-SNX2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SNX2 (sorting nexin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CTB-36H16.2; sorting nexin-2; transformation-related gene 9 protein; TRG-9
Description (eCommerce)
SNX2 (sorting nexin-2) belongs to the sorting nexin family whose members contain the phosphoinositide-binding phox (PX) domain. SNX2 is a component of the retromer complex which plays a role in protein sorting in the endocytic pathway. SNX2 may form oligomeric complexes with other family members [taken from NCBI Entrez Gene (Gene ID: 6643)].
Description (Vector)
SNX2 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with formin-binding protein 17, but its function is unknown. This protein may form oligomeric complexes with family members.
Gene ID
6643
Gene Name (eCommerce)
sorting nexin 2
Gene Name (Vector)
sorting nexin 2
Gene Symbol
SNX2
HGNC ID
HGNC:11173
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1560
ORF Size (bp)
1560 bp
Protein Name (eCommerce)
Sorting nexin-2
RefSeq ID
NM_003100
RefSeq Synonyms
NM_003100, NM_001278199, BC003382,
Research Areas
Golgi Apparatus,Signal Transduction,TGF-beta Signaling,Transport
Research Areas (Faceted)
signal_transduction,cell_biology,immunology,cell_biology
Species
human
Target Sentence
SNX2 (sorting nexin-2) belongs to the sorting nexin family whose members contain the phosphoinositide-binding phox (PX) domain. SNX2 is a component of the retromer complex which plays a role in protein sorting in the endocytic pathway. SNX2 may form oligomeric complexes with other family members [taken from NCBI Entrez Gene (Gene ID: 6643)].
UniGene ID
Hs.713554
UniProt ID (eCommerce)
O60749
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.