human SNAP23 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SNAP23.
shADV-223807
Ad-h-SNAP23-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SNAP23 (synaptosome associated protein 23). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HsT17016; SNAP-23; SNAP23A; SNAP23B
Description (Vector)
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Gene ID
8773
Gene Name (Vector)
synaptosome associated protein 23
Gene Symbol
SNAP23
HGNC ID
HGNC:11131
ORF Size (aa)
636
RefSeq ID
NM_003825
RefSeq Synonyms
NM_130798, NM_003825, BC022890, BC003686, BC000148,
Species
human
UniGene ID
Hs.511149
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.