human SLC25A27 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SLC25A27.
shADV-223251
Ad-h-SLC25A27-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SLC25A27 (solute carrier family 25 member 27). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
UCP4
Description (Vector)
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.
Gene ID
9481
Gene Name (Vector)
solute carrier family 25 member 27
Gene Symbol
SLC25A27
HGNC ID
HGNC:21065
ORF Size (aa)
738
RefSeq ID
NM_004277
RefSeq Synonyms
NM_004277, NM_001204052, NM_001204051, BC033091,
Species
human
UniGene ID
Hs.40510
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.