human SIRT4 shRNA silencing Adenovirus

Name 
Ad-h-SIRT4-shRNA
Cat No 
shADV-223018
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SIRT4.

shADV-223018
Ad-h-SIRT4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SIRT4 (sirtuin 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SIR2L4
Description (Vector)
SIRT4 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Gene ID
23409
Gene Name (Vector)
sirtuin 4
Gene Symbol
SIRT4
HGNC ID
HGNC:14932
ORF Size (aa)
945
RefSeq ID
NM_012240
RefSeq Synonyms
NM_012240, BC109320, BC109319,
Species
human
UniGene ID
Hs.50861

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.