human SIL1 shRNA silencing Adenovirus

Name 
Ad-h-SIL1-shRNA
Cat No 
shADV-223001
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SIL1.

shADV-223001
Ad-h-SIL1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SIL1 (SIL1 nucleotide exchange factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BAP; MSS; ULG5
Description (Vector)
SIL1 encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
Gene ID
64374
Gene Name (Vector)
SIL1 nucleotide exchange factor
Gene Symbol
SIL1
HGNC ID
HGNC:24624
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_022464
RefSeq Synonyms
NM_022464, NM_001037633, BC011568,
Species
human
UniGene ID
Hs.483521

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.