human SH3GLB1 shRNA silencing Adenovirus

Name
Ad-h-SH3GLB1-shRNA

Cat No
shADV-222907

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SH3GLB1.

shADV-222907

Ad-h-SH3GLB1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SH3GLB1 (SH3 domain containing GRB2 like endophilin B1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Bif-1; CGI-61; dJ612B15.2; PPP1R70

Description (Vector)

SH3GLB1 encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants.

Gene ID

51100

Gene Name (Vector)

SH3 domain containing GRB2 like endophilin B1

Gene Symbol

SH3GLB1

HGNC ID

HGNC:10833

ORF Size (aa)

1098

ORF Size (bp)

1098 bp

RefSeq ID

NM_016009

RefSeq Synonyms

NM_016009, NM_001206653, NM_001206652, NM_001206651, BC007455,

Species

human

UniGene ID

Hs.136309

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.