human SGK1 shRNA silencing Adenovirus

Name 
Ad-h-SGK1-shRNA
Cat No 
shADV-222850
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Human SGK1.

shADV-222850
Ad-h-SGK1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SGK1 (serum/glucocorticoid regulated kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SGK
Description (Vector)
SGK1 encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gene ID
6446
Gene Name (Vector)
serum/glucocorticoid regulated kinase 1
Gene Symbol
SGK1
HGNC ID
HGNC:10810
ORF Size (aa)
1296
ORF Size (bp)
1296 bp
RefSeq ID
NM_005627
RefSeq Synonyms
NM_005627, NM_001291995, NM_001143678, NM_001143677, NM_001143676, BC001263,
Species
human
UniGene ID
Hs.510078

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.