human SGCB shRNA silencing Adenovirus

Name 
Ad-h-SGCB-shRNA
Cat No 
shADV-222841
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SGCB.

shADV-222841
Ad-h-SGCB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SGCB (sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
A3b; LGMD2E; SGC
Description (Vector)
SGCB encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
Gene ID
6443
Gene Name (Vector)
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Gene Symbol
SGCB
HGNC ID
HGNC:10806
ORF Size (aa)
957
RefSeq ID
NM_000232
RefSeq Synonyms
NM_000232, BC020709,
Species
human
UniGene ID
Hs.438953

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.