human SFTPC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SFTPC.
shADV-222830
Ad-h-SFTPC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SFTPC (surfactant protein C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BRICD6; PSP-C; SFTP2; SMDP2; SP-C
Description (Vector)
SFTPC encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Gene ID
6440
Gene Name (Vector)
surfactant protein C
Gene Symbol
SFTPC
HGNC ID
HGNC:10802
ORF Size (aa)
594
RefSeq ID
NM_003018
RefSeq Synonyms
NM_003018, NM_001317780, NM_001317779, NM_001317778, NM_001172410, NM_001172357, BC005913,
Species
human
UniGene ID
Hs.1074
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.