human SFRS18 shRNA silencing Adenovirus

Name 
Ad-h-SFRS18-shRNA
Cat No 
shADV-222799
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PNISR.

shADV-222799
Ad-h-SFRS18-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PNISR (PNN interacting serine and arginine rich protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
69
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
arginine/serine-rich protein PNISR; bA98I9.2; C6orf111; HSPC306; PNN-interacting serine/arginine-rich protein; Serine/arginine-rich-splicing regulatory protein 130; serine-arginine-rich-splicing regulatory protein 130; SFRS18; splicing factor, arginine/serine-rich 130; splicing factor, arginine/serine-rich 18; SR-related protein; SR-rich protein; SRrp130
Description (eCommerce)
SFRS18/SRrp130 (splicing factor arginine/serine-rich 18) is a putative alternative splicing factor. It was identified as a factor that interacts with pinin (Pnn/DRS/memA), a cell-adhesion and nuclear protein of corneal epithelial cells. SFRS18/SRrp130 bears multiple arginine/serine-rich repeats found among the SR-related family of pre-mRNA processing factors. SFRS18/SRrp130 and pinin co-localize and are distributed as nuclear specks that correspond to the pre-splicing machinery.
Gene ID
25957
Gene Name (eCommerce)
PNN interacting serine and arginine rich protein
Gene Name (Vector)
PNN interacting serine and arginine rich protein
Gene Symbol
PNISR
HGNC ID
HGNC:21222
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2418
ORF Size (bp)
2418 bp
Protein Name (eCommerce)
Arginine/serine-rich protein PNISR
RefSeq ID
NM_032870
RefSeq Synonyms
NM_032870, NM_015491, NM_001322419, NM_001322418, NM_001322417, NM_001322416, NM_001322415, NM_001322414, NM_001322413, NM_001322412, NM_001322410, NM_001322408, NM_001322406, NM_001322405, BC172321,
Research Areas
RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
SFRS18/SRrp130 (splicing factor arginine/serine-rich 18) is a putative alternative splicing factor. It was identified as a factor that interacts with pinin (Pnn/DRS/memA), a cell-adhesion and nuclear protein of corneal epithelial cells. SFRS18/SRrp130 bears multiple arginine/serine-rich repeats found among the SR-related family of pre-mRNA processing factors. SFRS18/SRrp130 and pinin co-localize and are distributed as nuclear specks that correspond to the pre-splicing machinery.
UniGene ID
Hs.520287
UniProt ID (eCommerce)
Q8TF01

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.