human SFPQ shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SFPQ.
shADV-222779
Ad-h-SFPQ-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SFPQ (splicing factor proline and glutamine rich). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
100 kDa DNA-pairing protein; DNA-binding p52/p100 complex, 100 kDa subunit; epididymis secretory sperm binding protein; hPOMp100; polypyrimidine tract binding protein associated; polypyrimidine tract-binding protein-associated splicing factor; Polypyrimidine tract-binding protein-associated-splicing factor; POMP100; PPP1R140; protein phosphatase 1, regulatory subunit 140; PSF; PTB-associated splicing factor; PTB-associated-splicing factor; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); splicing factor proline/glutamine-rich; splicing factor, proline- and glutamine-rich
Description (eCommerce)
PSF/SFPQ is a multifunctional protein know to participate in a variety of nuclear processes and may function to link transcription and pre-mRNA processing. PSF/SFPQ bears an RNA recognition motif (RRM) further indicating its role in post-transcriptional processes. PSF has been shown to associate with p54nrb/NonO to modulate androgen receptor-mediated transcription. Additionally, it has recently been show to associate with XRN2 and p54nrb/NonO to facilitate pre-mRNA 3’ processing and transcription termination.
Gene ID
6421
Gene Name (eCommerce)
splicing factor proline and glutamine rich
Gene Name (Vector)
splicing factor proline and glutamine rich
Gene Symbol
SFPQ
HGNC ID
HGNC:10774
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2124
ORF Size (bp)
2124 bp
Protein Name (eCommerce)
Splicing factor, proline- and glutamine-rich
RefSeq ID
NM_005066
RefSeq Synonyms
NM_005066, BC051192,
Research Areas
DNA Damage/Repair,EGFR Signaling,Kinase/Phosphatase,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Signal Transduction,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
signal_transduction,genetics,transcription_translation,signal_transduction,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
PSF/SFPQ is a multifunctional protein know to participate in a variety of nuclear processes and may function to link transcription and pre-mRNA processing. PSF/SFPQ bears an RNA recognition motif (RRM) further indicating its role in post-transcriptional processes. PSF has been shown to associate with p54nrb/NonO to modulate androgen receptor-mediated transcription. Additionally, it has recently been show to associate with XRN2 and p54nrb/NonO to facilitate pre-mRNA 3’ processing and transcription termination.
UniGene ID
Hs.355934
UniProt ID (eCommerce)
P23246
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.