human SF1 shRNA silencing Adenovirus

Name 
Ad-h-SF1-shRNA
Cat No 
shADV-222754
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SF1.

shADV-222754
Ad-h-SF1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SF1 (splicing factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BBP; D11S636; mammalian branch point-binding protein; MBBP; splicing factor 1; transcription factor ZFM1; ZCCHC25; ZFM1; zinc finger gene in MEN1 locus; zinc finger protein 162; ZNF162
Description (eCommerce)
Splicing factor 1 (SF1) is a nuclear pre-mRNA splicing factor. SF1 specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly [taken from NCBI Entrez Gene (Gene ID: 7536)].
Description (Vector)
SF1 encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants.
Gene ID
7536
Gene Name (eCommerce)
splicing factor 1
Gene Name (Vector)
splicing factor 1
Gene Symbol
SF1
HGNC ID
HGNC:12950
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2022
ORF Size (bp)
2022 bp
Protein Name (eCommerce)
Splicing factor 1
RefSeq ID
NM_004630
RefSeq Synonyms
NM_201998, NM_201997, NM_201995, NM_004630, NM_001346410, NM_001346409, NM_001346364, NM_001346363, NM_001178031, NM_001178030, BC038446, BC020217, BC008724, BC008080,
Research Areas
Cell Cycle,Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Splicing factor 1 (SF1) is a nuclear pre-mRNA splicing factor. SF1 specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly [taken from NCBI Entrez Gene (Gene ID: 7536)].
UniGene ID
Hs.502829
UniProt ID (eCommerce)
Q15637

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.