human SENP5 shRNA silencing Adenovirus

Name 
Ad-h-SENP5-shRNA
Cat No 
shADV-222576
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SENP5.

shADV-222576
Ad-h-SENP5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SENP5 (SUMO1/sentrin specific peptidase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 (PubMed 16738315)).(supplied by OMIM, Jun 2009)
Gene ID
205564
Gene Name (Vector)
SUMO1/sentrin specific peptidase 5
Gene Symbol
SENP5
HGNC ID
HGNC:28407
ORF Size (aa)
2268
ORF Size (bp)
2268 bp
RefSeq ID
NM_152699
RefSeq Synonyms
NM_152699, NM_001308045, BC030705,
Species
human
UniGene ID
Hs.240770

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.