human RXRG shRNA silencing Adenovirus

Name
Ad-h-RXRG-shRNA

Cat No
shADV-222148

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RXRG.

shADV-222148

Ad-h-RXRG-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RXRG (retinoid X receptor gamma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

NR2B3; RXRC

Description (Vector)

RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described.

Gene ID

6258

Gene Name (Vector)

retinoid X receptor gamma

Gene Symbol

RXRG

HGNC ID

HGNC:10479

ORF Size (aa)

1392

ORF Size (bp)

1392 bp

RefSeq ID

NM_006917

RefSeq Synonyms

NM_006917, NM_001256571, NM_001256570, BC012063,

Species

human

UniGene ID

Hs.26550

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.