human RUVBL1 shRNA silencing Adenovirus

Name 
Ad-h-RUVBL1-shRNA
Cat No 
shADV-222123
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RUVBL1.

shADV-222123
Ad-h-RUVBL1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RUVBL1 (RuvB like AAA ATPase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP54; ECP-54; epididymis secretory sperm binding protein; INO80 complex subunit H; INO80H; NMP 238; NMP238; nuclear matrix protein 238; PONTIN; pontin 52; Pontin52; RuvB (E coli homolog)-like 1; ruvB-like 1; RuvB-like AAA ATPase; RVB1; TAP54-alpha; TATA binding protein interacting protein 49 kDa; TIH1; TIP49; TIP49A; TIP60-associated protein 54-alpha
Description (eCommerce)
RuvB-like 1 (RUVBL1) possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y265].
Gene ID
8607
Gene Name (eCommerce)
RuvB like AAA ATPase 1
Gene Name (Vector)
RuvB like AAA ATPase 1
Gene Symbol
RUVBL1
HGNC ID
HGNC:10474
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1371
ORF Size (bp)
1371 bp
Protein Name (eCommerce)
RuvB-like 1
RefSeq ID
NM_003707
RefSeq Synonyms
NM_003707, NM_001319086, NM_001319084, BC012886, BC002993,
Research Areas
Cancer,Cell Cycle,Cell Division,Chromatin Remodeling,Cytoskeleton,DNA Damage/Repair,Golgi Apparatus,Helicase Activity,Histone Modification,Signal Transduction,Spermatogenesis,Telomeric Maintenance,Transcription Factor/Regulator,Wnt Signaling
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,cell_cycle,transcription_translation,genetics,cell_biology,genetics,cell_biology,cell_cycle,genetics,transcription_translation,signal_transduction,developmental_biology
Species
human
Target Sentence
RuvB-like 1 (RUVBL1) possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y265].
UniGene ID
Hs.272822
UniProt ID (eCommerce)
Q9Y265

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.