human RUFY1 shRNA silencing Adenovirus

Name 
Ad-h-RUFY1-shRNA
Cat No 
shADV-222105
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RUFY1.

shADV-222105
Ad-h-RUFY1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RUFY1 (RUN and FYVE domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FYVE-finger protein EIP1; la-binding protein 1; rab4-interacting protein; RABIP4; RUN and FYVE domain-containing protein 1; ZFYVE12; zinc finger FYVE domain-containing protein 12
Description (eCommerce)
RUN and FYVE domain-containing protein 1 (RUFY1) binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96T51].
Description (Vector)
RUFY1 encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
80230
Gene Name (eCommerce)
RUN and FYVE domain containing 1
Gene Name (Vector)
RUN and FYVE domain containing 1
Gene Symbol
RUFY1
HGNC ID
HGNC:19760
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1803
ORF Size (bp)
1803 bp
Protein Name (eCommerce)
RUN and FYVE domain-containing protein 1
RefSeq ID
NM_025158
RefSeq Synonyms
NM_025158, NM_001040452, NM_001040451, BC032571,
Research Areas
Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
RUN and FYVE domain-containing protein 1 (RUFY1) binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96T51].
UniGene ID
Hs.306769
UniProt ID (eCommerce)
Q96T51

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.