human RPL9P25 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TIPIN.
shADV-221766
Ad-h-RPL9P25-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TIPIN (TIMELESS interacting protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CSM3 homolog; TIMELESS-interacting protein
Description (eCommerce)
Timeless-interacting protein (TIPIN) was originally isolated as a protein that interacts with timeless, a factor that plays a role in circadian rhythm and cell cycle checkpoint regulation. The TIM-TIPIN complex has been shown to coordinate the intra-S-phase checkpoint in response to UV-induced DNA damage. TIPIN is required for cell cycle arrest in response to DNA damage. It also interacts with RPA (replication protein A) on DNA and is able to slow down DNA chain elongation in response to UV-damage.
Gene ID
54962
Gene Name (eCommerce)
TIMELESS interacting protein
Gene Name (Vector)
TIMELESS interacting protein
Gene Symbol
TIPIN
HGNC ID
HGNC:30750
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
906
ORF Size (bp)
906 bp
Protein Name (eCommerce)
TIMELESS-interacting protein
RefSeq ID
NM_017858
RefSeq Synonyms
NM_017858, NM_001289986, BC000870,
Research Areas
Cell Cycle,Cell Division,DNA Damage/Repair,DNA Replication,Golgi Apparatus,Replication,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,cell_biology,cell_cycle
Species
human
Target Sentence
Timeless-interacting protein (TIPIN) was originally isolated as a protein that interacts with timeless, a factor that plays a role in circadian rhythm and cell cycle checkpoint regulation. The TIM-TIPIN complex has been shown to coordinate the intra-S-phase checkpoint in response to UV-induced DNA damage. TIPIN is required for cell cycle arrest in response to DNA damage. It also interacts with RPA (replication protein A) on DNA and is able to slow down DNA chain elongation in response to UV-damage.
UniGene ID
Hs.572318
UniProt ID (eCommerce)
Q9BVW5
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.