human RPL18A shRNA silencing Adenovirus

Name 
Ad-h-RPL18A-shRNA
Cat No 
shADV-221614
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RPL18A.

shADV-221614
Ad-h-RPL18A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RPL18A (ribosomal protein L18a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
60S ribosomal protein L18a; L18A; large ribosomal subunit protein eL20; ribosomal protein L18a-like protein
Description (eCommerce)
RPL18A/Ribosomal Protein L18a binds IPO9 with high affinity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q02543].
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.
Gene ID
6142
Gene Name (eCommerce)
ribosomal protein L18a
Gene Name (Vector)
ribosomal protein L18a
Gene Symbol
RPL18A
HGNC ID
HGNC:10311
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
531
Protein Name (eCommerce)
60S ribosomal protein L18a
RefSeq ID
NM_000980
RefSeq Synonyms
NM_000980, BC071920, BC066319, BC007512,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,metabolism,transcription_translation
Species
human
Target Sentence
RPL18A/Ribosomal Protein L18a binds IPO9 with high affinity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q02543].
UniGene ID
Hs.337766
UniProt ID (eCommerce)
Q02543

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.