human RNPC3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RNPC3.
shADV-221455
Ad-h-RNPC3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RNPC3 (RNA binding region (RNP1, RRM) containing 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RBM40; RNA-binding motif protein 40; RNA-binding protein 40; RNA-binding region-containing protein 3; RNP; SNRNP65; U11/U12 small nuclear ribonucleoprotein 65 kDa protein; U11/U12 snRNP 65 kDa protein; U11/U12 snRNP 65K; U11/U12-65K
Description (eCommerce)
RNA-binding protein 40, encoded for by RNPC3, participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns [taken from UniProtKB (Entry: Q96LT9)].
Description (Vector)
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
Gene ID
55599
Gene Name (eCommerce)
RNA binding region (RNP1, RRM) containing 3
Gene Name (Vector)
RNA binding region (RNP1, RRM) containing 3
Gene Symbol
RNPC3
HGNC ID
HGNC:18666
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1554
ORF Size (bp)
1554 bp
Protein Name (eCommerce)
RNA-binding protein 40
RefSeq ID
NM_017619
RefSeq Synonyms
NM_017619, BC010697,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
RNA-binding protein 40, encoded for by RNPC3, participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns [taken from UniProtKB (Entry: Q96LT9)].
UniGene ID
Hs.632430
UniProt ID (eCommerce)
Q96LT9
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.