human RNF7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RNF7.
shADV-221439
Ad-h-RNF7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RNF7 (ring finger protein 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CKBBP1; ROC2; SAG
Description (Vector)
RNF7 is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene ID
9616
Gene Name (Vector)
ring finger protein 7
Gene Symbol
RNF7
HGNC ID
HGNC:10070
ORF Size (aa)
342
RefSeq ID
NM_014245
RefSeq Synonyms
NM_183237, NM_014245, NM_001201370, BC008627, BC005966,
Species
human
UniGene ID
Hs.134623
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.