human RNASEH2C shRNA silencing Adenovirus

Name 
Ad-h-RNASEH2C-shRNA
Cat No 
shADV-221308
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human RNASEH2C.

shADV-221308
Ad-h-RNASEH2C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RNASEH2C (ribonuclease H2 subunit C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AGS3; AYP1
Description (Vector)
RNASEH2C encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene.
Gene ID
84153
Gene Name (Vector)
ribonuclease H2 subunit C
Gene Symbol
RNASEH2C
HGNC ID
HGNC:24116
ORF Size (aa)
495
RefSeq ID
NM_032193
RefSeq Synonyms
NM_032193, BC023588,
Species
human
UniGene ID
Hs.718438

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.