human RNASEH2C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RNASEH2C.
shAAV-221308
AAV-h-RNASEH2C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RNASEH2C (ribonuclease H2 subunit C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGS3; AYP1
Description (Vector)
RNASEH2C encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene.
Gene ID
84153
Gene Name (Vector)
ribonuclease H2 subunit C
Gene Symbol
RNASEH2C
HGNC ID
HGNC:24116
ORF Size (aa)
495
RefSeq ID
NM_032193
RefSeq Synonyms
NM_032193, BC023588,
Species
human
UniGene ID
Hs.718438
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.