human RGL2 shRNA silencing Adenovirus

Name 
Ad-h-RGL2-shRNA
Cat No 
shADV-221086
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RGL2.

shADV-221086
Ad-h-RGL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RGL2 (ral guanine nucleotide dissociation stimulator like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GDS-related protein; HKE1.5; KE1.5; RAB2L; ral guanine nucleotide dissociation stimulator-like 2; ralGDS-like 2; ralGDS-like factor; ras-associated protein RAB2L
Description (eCommerce)
Ral guanine nucleotide dissociation stimulator-like 2 (RGL2) is a probable guanine nucleotide exchange factor It is a putative effector of Ras and/or Rap. RGL2 associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15211].
Gene ID
5863
Gene Name (eCommerce)
ral guanine nucleotide dissociation stimulator like 2
Gene Name (Vector)
ral guanine nucleotide dissociation stimulator like 2
Gene Symbol
RGL2
HGNC ID
HGNC:9769
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2334
ORF Size (bp)
2334 bp
Protein Name (eCommerce)
Ral guanine nucleotide dissociation stimulator-like 2
RefSeq ID
NM_004761
RefSeq Synonyms
NM_004761, NM_001243738, BC032681,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Ral guanine nucleotide dissociation stimulator-like 2 (RGL2) is a probable guanine nucleotide exchange factor It is a putative effector of Ras and/or Rap. RGL2 associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15211].
UniGene ID
Hs.509622
UniProt ID (eCommerce)
O15211

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.