human RCC1 shRNA silencing Adenovirus

Name 
Ad-h-RCC1-shRNA
Cat No 
shADV-220937
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RCC1.

shADV-220937
Ad-h-RCC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RCC1 (regulator of chromosome condensation 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cell cycle regulatory protein; CHC1; Chromosome condensation protein 1; guanine nucleotide-releasing protein; RCC1-I; regulator of chromosome condensation; SNHG3-RCC1; SNHG3-RCC1 readthrough
Description (eCommerce)
RCC1 (regulator of chromosome condensation 1) is a chromatin associated guanine-nucleotide exchange factor (GEF) for the small nuclear G-protein, Ran. RCC1 is important to the nuclear pore transport process as well as chromosome condensation during S-phase of mitosis. The RCC1/Ran complex may also function to communicate the status of chromosomal replication to the events of cell cycle progression.
Gene ID
1104
Gene Name (eCommerce)
regulator of chromosome condensation 1
Gene Name (Vector)
regulator of chromosome condensation 1
Gene Symbol
RCC1
HGNC ID
HGNC:1913
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
Protein Name (eCommerce)
Regulator of chromosome condensation
RefSeq ID
NM_001269
RefSeq Synonyms
NM_001269, NM_001048199, NM_001048195, NM_001048194, BC069198, BC010067,
Research Areas
Cell Cycle,Cell Division,Chromatin Remodeling,Histone Modification,Host-Virus Interactions,Nuclear Import/Export
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,infectious_disease
Species
human
Target Sentence
RCC1 (regulator of chromosome condensation 1) is a chromatin associated guanine-nucleotide exchange factor (GEF) for the small nuclear G-protein, Ran. RCC1 is important to the nuclear pore transport process as well as chromosome condensation during S-phase of mitosis. The RCC1/Ran complex may also function to communicate the status of chromosomal replication to the events of cell cycle progression.
UniGene ID
Hs.469723
UniProt ID (eCommerce)
P18754

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.