human RCC1 shRNA silencing Adenovirus

Name 
Ad-h-RCC1-shRNA
Cat No 
shADV-220937
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RCC1.

shADV-220937
Ad-h-RCC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RCC1 (regulator of chromosome condensation 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cell cycle regulatory protein; CHC1; Chromosome condensation protein 1; guanine nucleotide-releasing protein; RCC1-I; regulator of chromosome condensation; SNHG3-RCC1; SNHG3-RCC1 readthrough
Description (eCommerce)
RCC1 (regulator of chromosome condensation 1) is a chromatin associated guanine-nucleotide exchange factor (GEF) for the small nuclear G-protein, Ran. RCC1 is important to the nuclear pore transport process as well as chromosome condensation during S-phase of mitosis. The RCC1/Ran complex may also function to communicate the status of chromosomal replication to the events of cell cycle progression.
Gene ID
1104
Gene Name (eCommerce)
regulator of chromosome condensation 1
Gene Name (Vector)
regulator of chromosome condensation 1
Gene Symbol
RCC1
HGNC ID
HGNC:1913
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
Protein Name (eCommerce)
Regulator of chromosome condensation
RefSeq ID
NM_001269
RefSeq Synonyms
NM_001269, NM_001048199, NM_001048195, NM_001048194, BC069198, BC010067,
Research Areas
Cell Cycle,Cell Division,Chromatin Remodeling,Histone Modification,Host-Virus Interactions,Nuclear Import/Export
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,infectious_disease
Species
human
Target Sentence
RCC1 (regulator of chromosome condensation 1) is a chromatin associated guanine-nucleotide exchange factor (GEF) for the small nuclear G-protein, Ran. RCC1 is important to the nuclear pore transport process as well as chromosome condensation during S-phase of mitosis. The RCC1/Ran complex may also function to communicate the status of chromosomal replication to the events of cell cycle progression.
UniGene ID
Hs.469723
UniProt ID (eCommerce)
P18754

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.