human RASA2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RASA2.
shADV-220759
Ad-h-RASA2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RASA2 (RAS p21 protein activator 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GAP1M
Description (Vector)
RASA2 is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger.
Gene ID
5922
Gene Name (Vector)
RAS p21 protein activator 2
Gene Symbol
RASA2
HGNC ID
HGNC:9872
ORF Size (aa)
2550
ORF Size (bp)
2550 bp
RefSeq ID
NM_006506
RefSeq Synonyms
NM_006506, NM_001303246, NM_001303245, BC172578, BC172285,
Species
human
UniGene ID
Hs.655941
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.