human RAMP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RAMP1.
shADV-220690
Ad-h-RAMP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RAMP1 (receptor activity modifying protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
RAMP1 is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Gene ID
10267
Gene Name (Vector)
receptor activity modifying protein 1
Gene Symbol
RAMP1
HGNC ID
HGNC:9843
ORF Size (aa)
447
RefSeq ID
NM_005855
RefSeq Synonyms
NM_005855, NM_001308353, BC000548,
Species
human
UniGene ID
Hs.471783
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.