human RAD51L1 shRNA silencing Adenovirus

Name 
Ad-h-RAD51L1-shRNA
Cat No 
shADV-220647
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RAD51B.

shADV-220647
Ad-h-RAD51L1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RAD51B (RAD51 paralog B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
R51H2; RAD51L1; REC2
Description (Vector)
RAD51B is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
Gene ID
5890
Gene Name (Vector)
RAD51 paralog B
Gene Symbol
RAD51B
HGNC ID
HGNC:9822
ORF Size (aa)
1155
ORF Size (bp)
1155 bp
RefSeq ID
NM_002877
RefSeq Synonyms
NM_133510, NM_133509, NM_002877, NM_001321821, NM_001321819, NM_001321818, NM_001321817, NM_001321815, NM_001321814, NM_001321812, NM_001321810, NM_001321809, BC030219,
Species
human
UniGene ID
Hs.172587

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.