human RABGGTB shRNA silencing Adenovirus

Name 
Ad-h-RABGGTB-shRNA
Cat No 
shADV-220610
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RABGGTB.

shADV-220610
Ad-h-RABGGTB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RABGGTB (Rab geranylgeranyltransferase beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Geranylgeranyl transferase type II subunit beta; geranylgeranyl transferase type-2 subunit beta; GGTase-II-beta; GGTB; Rab geranylgeranyltransferase beta subunit; Rab geranylgeranyltransferase subunit beta; Rab geranyl-geranyltransferase subunit beta; rab GG transferase beta; rab GGTase beta; type II protein geranyl-geranyltransferase subunit beta
Description (eCommerce)
Rab geranyl-geranyltransferase subunit beta (RABGGTB) catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53611].
Gene ID
5876
Gene Name (eCommerce)
Rab geranylgeranyltransferase subunit beta
Gene Name (Vector)
Rab geranylgeranyltransferase beta subunit
Gene Symbol
RABGGTB
HGNC ID
HGNC:9796
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
996
ORF Size (bp)
996 bp
Protein Name (eCommerce)
Geranylgeranyl transferase type-2 subunit beta
RefSeq ID
NM_004582
RefSeq Synonyms
NM_004582, BC020790,
Research Areas
Metabolism/Metabolic Process,Neurobiology
Research Areas (Faceted)
cell_biology,metabolism,neurobiology
Species
human
Target Sentence
Rab geranyl-geranyltransferase subunit beta (RABGGTB) catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53611].
UniGene ID
Hs.78948
UniProt ID (eCommerce)
P53611

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.