human PUM2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PUM2.
shADV-220394
Ad-h-PUM2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PUM2 (pumilio RNA binding family member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PUMH2; pumilio homolog 2; pumilio-2; PUML2
Description (eCommerce)
Pumilio 2 is a germline specific RNA binding protein that functions as a translational regulator by binding 3’ UTR elements. Pumilio 2 and its homolog Pumiolio 1 are highly evolutionarily conserved proteins that appear to function in germline maintenance. Pumilio 2 has been shown to interact with DAZL, a protein required for germ cell development.
Gene ID
23369
Gene Name (eCommerce)
pumilio RNA binding family member 2
Gene Name (Vector)
pumilio RNA binding family member 2
Gene Symbol
PUM2
HGNC ID
HGNC:14958
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3195
ORF Size (bp)
3195 bp
Protein Name (eCommerce)
Pumilio homolog 2
RefSeq ID
NM_015317
RefSeq Synonyms
NM_015317, NM_001282791, NM_001282790, NM_001282752, BC143550, BC112048, BC112046,
Research Areas
RNA Binding,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Pumilio 2 is a germline specific RNA binding protein that functions as a translational regulator by binding 3’ UTR elements. Pumilio 2 and its homolog Pumiolio 1 are highly evolutionarily conserved proteins that appear to function in germline maintenance. Pumilio 2 has been shown to interact with DAZL, a protein required for germ cell development.
UniGene ID
Hs.467824
UniProt ID (eCommerce)
Q8TB72
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.