human PTPRN shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTPRN.
shADV-220354
Ad-h-PTPRN-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPRN (protein tyrosine phosphatase, receptor type N). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N
Description (Vector)
PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Gene ID
5798
Gene Name (Vector)
protein tyrosine phosphatase, receptor type N
Gene Symbol
PTPRN
HGNC ID
HGNC:9676
ORF Size (aa)
2853
ORF Size (bp)
2853 bp
RefSeq ID
NM_002846
RefSeq Synonyms
NM_002846, NM_001199764, NM_001199763, BC070053, BC007713,
Species
human
UniGene ID
Hs.89655
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.