human PTPRE shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTPRE.
shADV-220342
Ad-h-PTPRE-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPRE (protein tyrosine phosphatase, receptor type E). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HPTPE; PTPE; R-PTP-EPSILON
Description (Vector)
PTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
Gene ID
5791
Gene Name (Vector)
protein tyrosine phosphatase, receptor type E
Gene Symbol
PTPRE
HGNC ID
HGNC:9669
ORF Size (aa)
2103
ORF Size (bp)
2103 bp
RefSeq ID
NM_006504
RefSeq Synonyms
NM_130435, NM_006504, NM_001323357, NM_001323356, NM_001323355, NM_001323354, NM_001316677, NM_001316676, BC050062,
Species
human
UniGene ID
Hs.127022
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.