human PTPN7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTPN7.
shADV-220328
Ad-h-PTPN7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPN7 (protein tyrosine phosphatase, non-receptor type 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
Description (Vector)
PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.
Gene ID
5778
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 7
Gene Symbol
PTPN7
HGNC ID
HGNC:9659
ORF Size (aa)
1200
ORF Size (bp)
1200 bp
RefSeq ID
NM_002832
RefSeq Synonyms
NM_080588, NM_002832, NM_001199797, BC001746,
Species
human
UniGene ID
Hs.402773
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.