human PTPN18 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTPN18.
shADV-220313
Ad-h-PTPN18-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPN18 (protein tyrosine phosphatase, non-receptor type 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BDP1; PTP-HSCF
Description (Vector)
PTPN18 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
26469
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 18
Gene Symbol
PTPN18
HGNC ID
HGNC:9649
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
RefSeq ID
NM_014369
RefSeq Synonyms
NM_014369, NM_001142370, BC052800,
Species
human
UniGene ID
Hs.591549
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.